Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic.
Abanoub Riad, Andrea Pokorná, Sameh Attia...
https://pubmed.ncbi.nlm.nih.gov/33916020Actively Recruiting
Age: 18Years +
All Genders
ID04834869
COVID-19 Vaccines Safety Tracking Global Consortium Study
Led by Masaryk University · Updated on 2022-04-06
30000
Participants Needed
14
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are actively monitoring the side effects of COVID-19 vaccines worldwide in healthcare workers, adults over 65, and schoolteachers. The study aims to estimate how common local and systemic side effects are for each vaccine brand, identify demographic and medical factors influencing side effects, and evaluate long-term consequences. It also compares the relative safety of different COVID-19 vaccines and examines how palliative drugs affect short-term side effect resolution. The project has two phases: a cross-sectional survey and a prospective cohort study. Phase A uses an online questionnaire to collect information about short-term side effects occurring within 30 days after vaccination, covering either the first or second dose. Phase B follows volunteers interested in reporting long-term side effects and vaccine effectiveness after booster doses over five years, starting in 2022. Multiple COVID-19 vaccines are included, such as Pfizer-BioNTech, Moderna, AstraZeneca, Sinovac, Sinopharm, Sputnik V, Janssen, CureVac, Novavax, and Covaxin. Participants provide self-reported data through validated online questionnaires about side effect onset, duration, and intensity. The study tracks local and systemic side effects within 30 days post-vaccination as primary outcomes, with unrecognized side effects as secondary outcomes. Volunteers are followed for long-term safety and vaccine effectiveness, with a total observation period extending up to five years. This ongoing monitoring helps researchers understand vaccine safety profiles and side effect patterns in different populations.
CONDITIONS
Brief Title
COVID-19 Vaccines Safety Tracking (CoVaST)
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Healthcare workers, adults over 65, or schoolteachers who have received a COVID-19 vaccine
- At least 18 years old
- Able to give informed consent independently
You will not qualify if you...
- Individuals who are not healthcare workers, adults over 65, or schoolteachers who received a COVID-19 vaccine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (online)
Surveillance
Duration - 30 days
Participants complete a self-administered online questionnaire to report short-term side effects occurring within 30 days after receiving a COVID-19 vaccine dose.
1 online questionnaire within 30 days after vaccination
Long-term Monitoring
Duration - 5 years
Participants who consent continue to report long-term side effects and vaccine effectiveness after booster doses using online questionnaires over five years.
Periodic online questionnaires after booster doses
Trial Site Locations
Total: 14 locations
1
American College of Physicians
Philadelphia, Pennsylvania, United States, 19106
Not Yet Recruiting
2
McMaster University
Hamilton, Ontario, Canada
Not Yet Recruiting
3
University of Split
Split, Croatia
Not Yet Recruiting
4
Masaryk University
Brno, Czechia
Actively Recruiting
5
University of Tartu
Tartu, Estonia
Not Yet Recruiting
6
Jimma University
Jimma, Ethiopia
Actively Recruiting
7
Justus-Liebig University Giessen
Giessen, Germany
Actively Recruiting
8
University of Ghana
Accra, Ghana
Not Yet Recruiting
9
Sinaloa's Pediatric Hospital
Culiacán, Mexico
Not Yet Recruiting
10
Medical University of Silesia
Katowice, Poland
Actively Recruiting
11
Nursing School of Coimbra
Coimbra, Portugal
Not Yet Recruiting
12
Irkutsk Scientific Center of Siberian Branch of Russian Academy of Sciences
Irkutsk, Russia, 664033
Actively Recruiting
13
University of Belgrade
Belgrade, Serbia, 11221
Actively Recruiting
14
University of Ljubljana
Ljubljana, Slovenia
Not Yet Recruiting
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Research Team
M
Miloslav Klugar, PhD
A
Abanoub Riad, DDS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
11
Frequently Asked Questions
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Published Research Related To This Trial
COVID-19 Vaccines Safety Tracking (CoVaST): Protocol of a Multi-Center Prospective Cohort Study for Active Surveillance of COVID-19 Vaccines' Side Effects.
Abanoub Riad, Holger Schünemann, Sameh Attia...
https://pubmed.ncbi.nlm.nih.gov/34360156