Actively Recruiting
CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-01-15
20
Participants Needed
2
Research Sites
52 weeks
Total Duration
On this page
Sponsors
A
Assistance Publique - Hôpitaux de Paris
Lead Sponsor
I
Institut National de la Santé Et de la Recherche Médicale, France
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research focuses on behavioral sensitization (BS) a specific behavioural disturbance in crack-cocaine addiction. The primary objective is to observe whether BS can be demonstrated in an ecological setting in crack dependent users by continuous actimetry for 3 weeks. It is planned to include 20 persons with a current crack-cocaine addiction with a preferential use of rapid administration route (intravenous or smoke), in a care institution: Fernand Widal Hospital. In the proposed research, the investigators will assess the movements of crack-cocaine dependent users in relation to consumption. They will have to wear continuously for 3 weeks an actimeter. They will also have 3 blood tests trying to identify biomarkers of BS.
CONDITIONS
Official Title
CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Current crack-cocaine use disorder defined as Severe Intensity Use Disorder (6 or more DSM5 criteria) with preferential use of rapid administration route (intravenous or smoked)
- Self-identified male or female (10 males and 10 females planned)
- Negative pregnancy test for females and use of effective contraception
- Affiliated with a social security plan (or PUMA or CSS or AME)
- Signed informed consent and commitment to 3-week follow-up
- Weight greater than 40 kg
You will not qualify if you...
- Psychiatric disorder or symptoms that are not currently stabilized
- Minor or under protective supervision (curatorship or guardianship)
- In care at the request of a judicial authority (therapeutic injunction, classification with orientation)
- Pregnant or breastfeeding women
- Insufficient proficiency in French or English
- Weight less than 40 kg
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Centre 001_Hôpital Fernand Widal
Paris, France, 75010
Actively Recruiting
2
Hôpital Fernand Widal
Paris, France, F75010
Actively Recruiting
Research Team
F
Florence Vorspan, MD, PhD
CONTACT
F
Florence Vorspan, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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