Actively Recruiting
Creation of a Database of Healthy Subjects With 18FDG PET Brain Imaging as Part of the MOBILE Project (Multimodal Whole-Brain Imaging in Epilepsy)
Led by Assistance Publique Hopitaux De Marseille · Updated on 2025-05-16
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are creating a database of healthy adult subjects aged 18 to 65 years to study brain structure and function using advanced imaging techniques. This project, part of the European Human Brain Project, focuses on healthy individuals to better understand brain activity and metabolism through a multimodal approach involving MRI, PET, and electrophysiology. The goal is to provide valuable data for scientific collaboration on epilepsy and brain health. Participants will undergo a 18F-FDG PET brain imaging exam, which measures glucose metabolism in the brain by using a small amount of radioactive tracer injected intravenously. The scan lasts about 45 minutes and captures a three-dimensional image at rest, allowing researchers to quantify brain glucose consumption and connectivity. This is a non-therapeutic study involving a single imaging procedure performed at baseline, with a follow-up measurement planned 24 months later. During the study, participants will be monitored through imaging and assessments of cerebral glucose consumption and metabolic connectivity at baseline and after 24 months. The PET scans are part of routine clinical procedures with established safety profiles, and all participants must provide informed consent. The study lasts over two years, including the initial scan and long-term follow-up, aiming to enhance understanding of healthy brain metabolism and function.
CONDITIONS
Brief Title
Creation of a Database of Healthy Subjects With 18FDG PET Brain Imaging as Part of the MOBILE Project (Multimodal Whole-Brain Imaging in Epilepsy)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female or male, aged over 18 and under 65 years
- Free of general illness, psychiatric disorders, or brain-related diseases
- Not taking chronic medications, especially psychotropic drugs
- No history of alcoholism or drug addiction
- No contraindications to PET imaging (not pregnant or breastfeeding)
- Covered by social security
- Able to understand and sign informed consent
You will not qualify if you...
- Under 18 years old
- Pregnant or breastfeeding women
- Women of childbearing age without contraception
- Any contraindication to PET imaging
- Adults under legal protection measures according to French law
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Baseline and 24 months
Participants undergo brain imaging examinations to assess cerebral glucose consumption and metabolic connectivity.
2 visits (in-person)
Duration - 24 months
Participants are followed over 24 months to observe changes in brain imaging outcomes.
1 follow-up visit at 24 months
Trial Site Locations
Total: 1 location
1
Hopital de la Timone
Marseille, France, 13354
Actively Recruiting
Research Team
E
Eric GUEDJ, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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