Actively Recruiting

Age: 18Years +
All Genders
NCT06898762

Creation of a National Multicenter Platform for the Study of Inflammatory Myocardial Disease: Pre-MYO Cohort

Led by Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia · Updated on 2025-03-27

3000

Participants Needed

1

Research Sites

299 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objectives of this project are: 1) to comprehensively characterize a large national cohort of patients with suspected myocarditis, their clinical phenotype, care management, blood and imaging biomarkers, epidemiological, environmental and genetic data; 2) to retrospectively validate the accuracy of the new hsa-RNA-Chr8:96 biomarker for the diagnosis of myocarditis compared to conventional diagnosis; 3) to identify acquired and inherited mutations, and their interaction with the environment, which explain the susceptibility to myocarditis, its severity and response to treatment; 4) to study the lower incidence in women and the influence of age, considering socio-health and genetic factors.

CONDITIONS

Official Title

Creation of a National Multicenter Platform for the Study of Inflammatory Myocardial Disease: Pre-MYO Cohort

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presence of at least one compatible symptom and at least one objective finding in diagnostic tests, according to the European Society of Cardiology consensus
  • Symptoms include acute chest pain, breathlessness on exertion or at rest (up to 1 year), unexplained palpitations or arrhythmias, sudden death recovered, or unexplained cardiogenic shock
  • Diagnostic findings include ECG changes (new AV block, bundle branch block, ST segment changes, T wave inversion), elevated TnI/TnT, heart muscle contractility alterations, or positive cardiac MRI Lake Louise criteria
  • Patients who have given their informed consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

HCUVA

Murcia, Murcia, Spain, 30120

Actively Recruiting

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Research Team

D

Domingo Pascual Figal, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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