Registry Study to Track Effectiveness of Genicular Artery Embolization for Knee Osteoarthritis Pain Relief

What this Trial Is About

Knee osteoarthritis KOA is a common and disabling condition characterized by pain, stiffness, and loss of joint function, affecting over 15 million people in the US. This research aims to create a prospective registry of fewer than 100 patients to evaluate the effectiveness of genicular artery embolization GAE in reducing knee pain over time, measured by the Western Ontario and McMaster Universities Osteoarthritis Index WOMAC score. The study is observational and sponsored by the University of Chicago. GAE is a minimally invasive procedure that uses live X-ray guidance to block blood flow in specific arteries around the knee believed to contribute to inflammation and pain. All enrolled patients will undergo GAE and be followed for one year after their procedure to observe changes. The study also plans to use MRI scans as an imaging biomarker to assess positive changes in the knees condition after treatment. Participants will be monitored for one year from their procedure date, with regular assessments of knee pain using the WOMAC score and tracking of any adverse events related to GAE. The registry will collect data to better understand the procedures effects and safety over a longer period and larger sample size, potentially informing a future controlled trial. The total participation time is one year per patient.

Creation of a Prospective Data Collecting Registry for Genicular Artery Embolization for Arthritis