Actively Recruiting
CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD
Led by Henan Institute of Cardiovascular Epidemiology · Updated on 2026-04-06
2000
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main objective of this study is to demonstrate whether the combination of chronic remote ischemic conditioning and mindfulness therapy can reduce cardiovascular adverse events in patients with incomplete revascularization of coronary artery disease.
CONDITIONS
Official Title
CRIC Combined With MFT for Cardiovascular Adverse Events in Patients With Incomplete Revascularization of CAD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with coronary artery disease without complete revascularization (at least one vessel with over 90% stenosis and reduced blood flow)
- Symptoms of myocardial ischemia such as resting or exertional angina, chest tightness, or shortness of breath
You will not qualify if you...
- Age under 18 years
- Heart failure with NYHA class IV or left ventricular ejection fraction less than 30%
- Creatinine clearance less than 15 mL/min or requiring dialysis
- Myocardial diseases like hypertrophic or dilated cardiomyopathy
- Uncontrolled or recurrent arrhythmic events
- Poorly controlled high blood pressure (systolic over 180 mm Hg or diastolic over 110 mm Hg)
- Active liver disease or persistent elevation of liver enzymes
- Unexplained high creatine kinase levels or muscle disease
- Planned or expected cardiac surgery or revascularization before randomization
- History of active cancer treatment within the past 3 years
- Diagnosed or suspected vascular malformations or thrombosis in upper extremities
- Hearing impairment preventing mindfulness therapy
- Current participation in another drug or device study or recent investigational treatment
- Life-threatening comorbid conditions expected to cause death within a year (excluding cardiovascular diseases)
- History of major organ transplant
- Major active uncontrolled diseases or medical conditions interfering with study participation
- Unlikely to complete follow-up or comply with study requirements
- Alcoholism or substance abuse history with inability or unwillingness to stop during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai Central China Cardiovascular Hospital
Zhengzhou, Henan, China, 450000
Actively Recruiting
Research Team
Q
Quan Guo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
4
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