Effects of Crocus Sativus Tepals Water Extract on Blood Sugar and Metabolic Health in Adults With Obesity or Prediabetes

What this Trial Is About

This research aims to evaluate the immediate effects of drinking a cold water extract made from Crocus sativus flower petals on blood sugar levels and other factors related to metabolic health in adults with obesity andor prediabetes. It investigates whether taking this extract before a meal improves blood sugar response, influences insulin levels, and increases resting energy use. The study is an early-phase, randomized clinical trial led by the University of Primorska. Participants will attend two visits to the research center. On one visit, they will drink 200 mL of cold Crocus sativus tepals extract prepared overnight, and on the other, they will drink 200 mL of cold water, in random order. Both drinks are consumed 5 minutes before eating a standard meal of 100 g white bread. There is at least a 7-day break between visits to clear the effects of the first treatment. During each visit, participants will have body measurements taken and resting metabolic rate and blood pressure assessed. Blood samples will be collected three times before eating fasting, and then 60 and 120 minutes after the meal. Researchers will closely monitor glucose levels, insulin, resting metabolism, and blood pressure to understand the extracts effects on metabolic health over the two-week study period.

Crocus Sativus Tepals Water Extract in Obesity and Prediabetes