Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 65Years
All Genders
NCT03794076

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

Led by Vishwajit Nimgaonkar, MD PhD · Updated on 2026-03-19

160

Participants Needed

1

Research Sites

478 weeks

Total Duration

On this page

Sponsors

V

Vishwajit Nimgaonkar, MD PhD

Lead Sponsor

S

Stanley Medical Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a double blind adjunctive randomized controlled trial for schizophrenia using cromoglicate.

CONDITIONS

Official Title

Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent
  • Both genders, ages 18-60 years
  • Diagnosis of schizophrenia or schizoaffective disorder according to DSM V
  • Treated with the same antipsychotic drug for at least 60 days and stable dose for more than 1 month
  • PANSS total score of 60 or higher and score 4 or more on one or more positive syndrome items (P1-P7)
  • Preference for patients with psychosis duration less than 7 years
Not Eligible

You will not qualify if you...

  • Illicit substance use in the last 30 days or dependence in 6 months, except methadone for opioid withdrawal
  • History or current medical or neurological illness causing unstable course, except well-controlled epilepsy for at least 6 months
  • Pregnancy
  • History of immune disorders, HIV infection, or use of immune suppressants or modulators such as steroids
  • Current or prior treatment with cromoglycate or known hypersensitivity to cromoglycate
  • Intellectual disability as defined by DSM V

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15213

Actively Recruiting

Loading map...

Research Team

V

Vishwajit L Nimgaonkar, M.D., Ph.D.

CONTACT

M

Maribeth A Wesesky, BPS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here