Actively Recruiting
Effectiveness of Non-Surgical Mechanical Therapy of Peri-Implantitis With or Without Prosthetic Crown Removal: A Randomized Controlled Trial
Led by G. d'Annunzio University · Updated on 2026-05-07
36
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how removing the prosthetic crown affects non-surgical mechanical treatment for implants with peri-implantitis. The goal is to compare clinical and radiographic changes at baseline and after 3, 6, and 12 months. The main measure is the average probing depth around the implant, with additional focus on gum recession, bone levels, bleeding scores, and patient factors. The study has two groups: one where the prosthetic crown is temporarily removed before treatment to allow better access for cleaning, and another where the crown remains in place during therapy. Both groups receive mechanical debridement under local anesthesia using sonic and ultrasonic devices with thin tips and Gracey curettes, following clinical guidelines. After cleaning, crowns are replaced in the removal group, and all patients get oral hygiene instructions. Participants will be assessed through clinical exams and radiographic imaging at specified intervals up to one year. Researchers will measure gum and bone changes, bleeding, and implant pocket depth to evaluate treatment effects. Safety and adherence will be monitored throughout, with a total study duration of 12 months from enrollment to final evaluation.
CONDITIONS
Brief Title
Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with at least one implant diagnosed with peri-implantitis
- Patients with a removable crown on the implant affected by peri-implantitis
- Patients who have not received non-surgical peri-implant therapy in the previous 6 months
- Patients who have not taken systemic antibiotic therapy in the previous 3 months
You will not qualify if you...
- Full-Mouth Plaque Score (FMPS) greater than 30% at the time of non-surgical therapy
- Pregnant or breastfeeding women
- Relevant medical history that could affect the outcome of therapy, as judged by the clinician
- Smoking more than 10 cigarettes per day
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 year
Participants receive non-surgical peri-implant therapy with or without temporary removal of the prosthetic crown. Mechanical cleaning of the peri-implant tissues is performed under local anesthesia using sonic and ultrasonic devices and curettes. Oral hygiene instructions and reinforcement are provided.
Trial Site Locations
Total: 1 location
1
Dental Clinic, Department of Innovative Technologies in Medicine and Dentistry, 'G. D'Annunzio' University of Chieti-Pescara
Chieti, Chieti, Italy, 66100
Actively Recruiting
Research Team
M
Michele Paolantonio, DDS, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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