Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07391202

Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial

Led by G. d'Annunzio University · Updated on 2026-05-07

36

Participants Needed

1

Research Sites

66 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this single-blind, randomized controlled clinical trial is to evaluate whether removal of the prosthetic crown influences the clinical effectiveness of non-surgical mechanical therapy in implants affected by peri-implantitis. The study is designed to compare changes in several clinical and radiographic parameters between baseline and follow-up examinations at 3, 6, and 12 months. The primary outcome measure will be the mean peri-implant probing depth (PIPD). Secondary outcomes will include changes in gingival recession (REC), radiographic marginal bone level (MBL), modified bleeding index (mBI), and additional patient-related variables.

CONDITIONS

Official Title

Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with at least one implant diagnosed with peri-implantitis
  • Patients with a removable crown on the implant affected by peri-implantitis
  • Patients who have not received non-surgical peri-implant therapy in the previous 6 months
  • Patients who have not taken systemic antibiotic therapy in the previous 3 months
Not Eligible

You will not qualify if you...

  • Full-Mouth Plaque Score greater than 30% at time of therapy
  • Pregnant or breastfeeding women
  • Relevant medical history that could affect treatment outcome, as judged by the clinician
  • Smoking more than 10 cigarettes per day

AI-Screening

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Trial Site Locations

Total: 1 location

1

Dental Clinic, Department of Innovative Technologies in Medicine and Dentistry, 'G. D'Annunzio' University of Chieti-Pescara

Chieti, Chieti, Italy, 66100

Actively Recruiting

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Research Team

M

Michele Paolantonio, DDS, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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