A Phase II Program Testing Cruciferous Vegetable Eating to Lower Bladder Cancer Recurrence and Progression in Adults With Early-Stage Non-Muscle Invasive Bladder Cancer

What this Trial Is About

Researchers are evaluating a healthy eating program aimed at reducing cancer recurrence and progression in patients with non-muscle invasive bladder cancer NMIBC. The study focuses on increasing intake of cruciferous vegetables, such as cabbage, kale, and broccoli, which contain compounds called isothiocyanates ITCs that may have anticancer effects. This phase II trial seeks to understand if this dietary approach can improve outcomes for men and women diagnosed with early-stage bladder cancer. The trial compares two versions of the POW-R Health program the core program alone and the core program plus a maintenance component. Participants are randomly assigned to one of these groups to assess the levels of urinary ITCs and cruciferous vegetable intake over up to 24 months. The program includes behavioral dietary intervention and live telephone calls to support increased consumption of these vegetables. Participants will be involved for up to two years, during which their urinary ITC levels and dietary intake of cruciferous vegetables will be regularly monitored. The study includes discussions with community advisory board members and ongoing communication through phone calls. Researchers will assess the programs impact on diet and cancer-related biomarkers to understand its potential benefits in reducing bladder cancer recurrence or progression.

A Cruciferous Vegetable Eating Program for the Reduction of Cancer Recurrence and Progression in Patients With Non-muscle Invasive Bladder Cancer