Actively Recruiting
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2026-04-29
320
Participants Needed
3
Research Sites
288 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with subarachnoid hemorrhage are prone to suffer from dysnatriemia. Evidence shows that hyponatriemia is associated with increased incidence of vasospasm, brain swelling and mortality in these patients. Patients with subarachnoid hemorrhage often require large amounts of iv fluids in order to maintain euvolemia and support cardiocirculatory function. Prior evidence shows that the type of infusion fluid significantly influences blood sodium content. Hence, this study evaluated whether the sodium content of the infusion solution impacts mortality and morbidity in patients with subarachnoid hemorrhage.
CONDITIONS
Official Title
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients diagnosed with non-traumatic subarachnoid hemorrhage
You will not qualify if you...
- Patients with major intracranial trauma
- Diagnosis of AV-malformation as cause of subarachnoid hemorrhage on imaging
- More than 24 hours since subarachnoid hemorrhage diagnosis by CT, MRI, or angiography
- Patients with clear therapy limitations at hospital admission (e.g., ICU admission for organ donation evaluation)
- Patients who decline to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Department of perioperative Intensive Care Medicine
Sankt Gallen, Canton of St. Gallen, Switzerland, 9007
Actively Recruiting
2
Department of Intensive Care, Bern University Hospital and University of Bern, Bern, Switzerland
Bern, Switzerland, 3010
Actively Recruiting
3
Department of Intensive Care Medicine
Geneva, Switzerland, 1205
Actively Recruiting
Research Team
A
Anna S Messmer, MD
CONTACT
R
Research Nurses Department of Intensive Care
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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