Actively Recruiting

Phase 4
Age: 18Years - 88Years
All Genders
Healthy Volunteers
NCT05758701

CT TAVR Abdomen Study

Led by University of Maryland, Baltimore · Updated on 2025-04-24

164

Participants Needed

1

Research Sites

179 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.

CONDITIONS

Official Title

CT TAVR Abdomen Study

Who Can Participate

Age: 18Years - 88Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled to receive TAVR abdominal CT
Not Eligible

You will not qualify if you...

  • Cannot undergo CT scan
  • Allergy to intravenous contrast not controlled by steroids or Benadryl
  • Glomerular filtration rate (GFR) less than 30

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Maryland Medical Center

Baltimore, Maryland, United States, 21201

Actively Recruiting

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Research Team

V

Vikas Kundra, M.D., Ph.D

CONTACT

R

Rosy Njonkou, M.S.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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