Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT05052671

ctDNA Assay in Patients With Resectable Pancreatic Cancer

Led by University of Oklahoma · Updated on 2026-03-05

50

Participants Needed

2

Research Sites

340 weeks

Total Duration

On this page

Sponsors

U

University of Oklahoma

Lead Sponsor

N

Natera, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to determine the proportion of positive ctDNA -freely circulating tumor DNA fragments found in the blood plasma- in patients with pancreatic cancer and to better understand the relationship between possible ctDNA biomarkers and patient survival. A successful study may provide preliminary evidence that helps improve future patient care through targeted diagnostics, prognosis, and/or treatment.

CONDITIONS

Official Title

ctDNA Assay in Patients With Resectable Pancreatic Cancer

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Newly diagnosed exocrine pancreatic cancer confirmed by pathology or imaging
  • Resectable or borderline resectable pancreatic cancer as defined by NCCN guidelines
  • At least 18 years old at the time of informed consent
  • ECOG Performance Status of 0 or 1
  • Eligible for neoadjuvant chemotherapy, chemoradiotherapy, or upfront surgery
  • Able to provide written informed consent and HIPAA authorization
  • Life expectancy of at least 6 months
Not Eligible

You will not qualify if you...

  • Pancreatic tumors confirmed as neuroendocrine or other types of malignancies
  • Positive pregnancy test, pregnant, or breastfeeding
  • Any significant and/or uncontrolled cardiac abnormality compromising safety or study outcome
  • Locally advanced or metastatic pancreatic cancer

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

University of Oklahoma

Oklahoma City, Oklahoma, United States, 73117

Actively Recruiting

2

Stephenson Cancer Center- Tulsa

Tulsa, Oklahoma, United States, 74104

Not Yet Recruiting

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Research Team

L

Lead Nurse

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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ctDNA Assay in Patients With Resectable Pancreatic Cancer | DecenTrialz