Actively Recruiting

Phase Not Applicable
Age: 10Years - 17Years
All Genders
NCT07160621

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Led by St. Jude Children's Research Hospital · Updated on 2026-04-23

228

Participants Needed

1

Research Sites

177 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to determine if an adapted mobile cognitive behavioral therapy (CBT) app (WebMAP Onc) is more effective than standard pain education in reducing chronic pain and improving daily functioning in adolescent survivors of pediatric cancer. This randomized study led by St. Jude Children's Research Hospital will involve 228 participants (114 adolescent survivors and 114 caregivers) across four U.S. hospitals. Outcomes include pain reduction, improved function, and the role of social determinants of health. Assessments occur at baseline, post-treatment, and 3-month follow-up.

CONDITIONS

Official Title

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer: A Randomized Clinical Trial

Who Can Participate

Age: 10Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescent Participants

    • 10-17-year-old survivors of childhood cancer or those who received cancer directed therapies (e.g., Langerhan's Histiocytosis)
    • At least one-year post treatment completion
    • Pain present for 3 months or longer
    • Pain interfering with at least one area of daily functioning
  • Parent/Caregiver Participants

    • ≥ 18 years of age
    • Legally authorized to provide informed consent for the adolescent participant
Not Eligible

You will not qualify if you...

  • Adolescent Participants

    • Serious comorbid psychiatric condition

    • Current substance abuse as determined by the Substance Use Screening Questionnaire

    • History of development delay or significant cognitive impairment

      • Note: A participant who completed the feasibility study (ADAPTED) cannot participate in the subsequent clinical trial (ADAPTED2)
  • Parent/Caregiver Participants

    • Not fluent in English or Spanish
    • Unable to provide consent for own participation or for the participation of the adolescent participant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105

Actively Recruiting

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Research Team

T

Tara Brinkman, PhD

CONTACT

T

Tara Brinkman

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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