HealthyCells A Culturally Tailored Smartphone Program to Help African American Adults Quit Smoking and Reduce Sitting Time
Led by University of Oklahoma · Updated on 2026-05-01
30
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to develop and test a culturally tailored smartphone app called HealthyCells to help African American smokers quit smoking and reduce sedentary behavior. African Americans have higher quit attempts but lower success rates compared to other groups. By integrating two proven smartphone interventions, the study seeks to address barriers and promote cessation and activity using tailored content that considers cultural strengths and challenges.
HealthyCells combines a smoking cessation app with features like facial recognition to verify smoking status twice daily using carbon monoxide breath samples, and activity monitoring via a Google smartwatch. The app sends real-time prompts to encourage movement after 30 minutes of sitting and delivers motivational messages twice daily to support quitting and reduce sedentary time. The study includes a pilot phase with 15 African American smokers to refine the app, followed by a main phase where 30 participants will use HealthyCells during a planned quit attempt.
Participants will engage in smoking status assessments and activity monitoring remotely, with rewards for abstinence based on biochemical verification at 8 weeks. Sedentary time will be measured by accelerometer for 7 days before quitting and 7 days at 8 weeks post-quit. The research team will evaluate smoking abstinence rates and changes in sedentary behavior to determine the apps feasibility. The total study participation is focused on the 8-week period post-quit date, with frequent assessments and feedback via the app.
CONDITIONS
Brief Title
A Culturally Tailored Smartphone Application for African American Smokers
Research Team
A
Adam C Alexander, PhD
A
Ashley Krukowski, MPA, CRA
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National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
How This Trial Compares With Other Options
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
Factors
HealthyCells app
Standard cessation support
What it is
A smoking cessation smartphone app culturally tailored for African American adults, combined with NRT, app use, and counseling, tested in a pilot trial of 30 participants
Standard cessation support generally includes nicotine replacement therapy plus counseling based on established clinical practice
Role in the trial
Participants used this culturally tailored app along with other support components during their quit attempt
Not evaluated in this trial
Primary use
To support smoking cessation in African American adult smokers using a culturally adapted digital intervention
To help people quit smoking using evidence-based methods such as NRT plus counseling
How it is given or performed
Delivered via smartphone using tailored messages, videos, images, app features plus counseling and NRT support
Typically involves use of nicotine gum, patch, or lozenge and support from a counselor or quitline
Evidence status
Feasibility and user feedback being studied; effectiveness not yet established
Effectiveness supported by multiple randomized trials of NRT and counseling
Important risks
Potential allergic reaction or contraindication to NRT if used without provider approval
Possible side effects of NRT (e.g., skin irritation, sleep disturbance), generally well studied
Important limitations
Small pilot sample without control group limits conclusions about effectiveness
Not directly tested in this pilot study; real‑world adherence may vary
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
Who Can Participate
Age: 18Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Must be 18 years of age or older
Must identify as Black or African American
Must smoke at least 5 cigarettes or cigarette equivalents daily
Must be willing to use nicotine replacement therapy, a smartphone watch and app, and a smoking cessation counselor
Must be willing to quit smoking within the next 3 weeks
Must have a carbon monoxide level greater than 6 ppm at app activation
Must be physically inactive, defined as less than 150 minutes of moderate or 75 minutes of vigorous aerobic activity per week
You will not qualify if you...
Does not give permission to administer screening survey
Does not understand or speak English
Is not a U.S. citizen or permanent resident
Does not use tobacco products
Does not want to provide social security number, residency status, or employee status
Is not willing to abstain from smoking marijuana or cannabis during the quit attempt
Is not willing to upload a picture of their tobacco product
Is not ready to quit smoking (score 4 or lower on readiness ladder)
Has a medical condition preventing use of nicotine replacement therapy without healthcare provider approval
Has had a serious allergic reaction or side effect from nicotine replacement therapy
Does not give permission to collect contact information
Is currently physically active beyond the activity limits defined for the study
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) to assess eligibility
Treatment
Duration - 8 weeks from quit date
Participants use the HealthyCells smartphone app to support smoking cessation and reduce sedentary behavior. The app prompts twice-daily smoking status assessments with facial recognition and delivers activity prompts during prolonged sedentary periods. Motivational messages are sent twice daily to encourage quitting and physical activity.
Twice-daily remote assessments and continuous app engagement
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Published Research Related To This Trial
An mHealth Intervention With Financial Incentives to Promote Smoking Cessation and Physical Activity Among Black Adults: Protocol for a Feasibility Randomized Controlled Trial.
Adam Alexander, Michael Businelle, Marshall Cheney...