Actively Recruiting
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Led by Auburn University · Updated on 2025-02-14
64
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized placebo controlled trial is to examine mood disturbance and serum brain derived neurotrophic factor (BDNF) in people (age 18-50) with DASS-21 subscale scores \>9. The main questions it aims to answer are: Does curcumin and EGCG supplementation improve mood disturbance symptomology? Does curcumin and EGCG supplementation increase serum BDNF? Researchers will compare intervention versus placebo. Participants will consume an 8-week supplement of both: * 1,330mg/day curcumin * 350mg/day epigallocatechin gallate (EGCG)
CONDITIONS
Official Title
Curcumin and EGCG Supplementation to Improve Serum BDNF and Mood Disturbance
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults age 18-50
- Depression subscale score greater than 9/21 on the DASS-21
- No changes in medications or supplements in the past 3 months
- Able to read and speak English
You will not qualify if you...
- Currently consume curcumin or green tea daily
- Currently pregnant, nursing, or trying to become pregnant
- Currently diagnosed with a perimenopausal disorder
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Auburn University School of Kinesiology
Auburn, Alabama, United States, 36849
Actively Recruiting
Research Team
A
Aidan Cavanah, MSc
CONTACT
A
Andrew Fruge, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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