Actively Recruiting

Phase 1
Phase 2
Age: 40Years - 89Years
All Genders
Healthy Volunteers
NCT05774704

Curcumin and Retinal Study

Led by Texas Tech University Health Sciences Center · Updated on 2026-01-13

60

Participants Needed

1

Research Sites

175 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To test how two weeks of curcumin supplementation would cross the blood brain barrier (BBB) and attach to amyloid beta proteins, to assess the feasibility (safety and bioavailability), and to explore the resulting abundance/composition of gut microbiota.

CONDITIONS

Official Title

Curcumin and Retinal Study

Who Can Participate

Age: 40Years - 89Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female between 40 and 89 years old
  • Diagnosed with amyloid beta deposits in the retina (peripheral superior quadrants) confirmed within 6 months or by ophthalmic exam after consent
  • No existing liver or kidney disease by self-report
Not Eligible

You will not qualify if you...

  • Have ocular diseases such as macular degeneration or severe diabetic retinopathy
  • Used systemic antibiotics within 1 month before starting the study
  • Taken turmeric or curcumin products within 2 weeks before starting the study
  • Known allergy to black pepper
  • Pregnant or breastfeeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Texas Tech University Health Sciences Center

Lubbock, Texas, United States, 79430

Actively Recruiting

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Research Team

C

Chwan-Li (Leslie) Shen, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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