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Ventilation Practices During General Anesthesia in Children Up to 16 Years and Their Link to Lung Complications After Surgery An International Study Observing Mechanical Ventilation Methods and Outcomes
Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2025-04-09
10000
Participants Needed
4
Research Sites
1 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to better understand the use of mechanical ventilation during general anesthesia in children aged 16 years and younger. It focuses on how different ventilation settings may relate to the development of postoperative pulmonary complications PPCs, which are common and can lead to longer hospital stays and increased costs. The study addresses the current lack of guidance and variation in ventilation practices for pediatric patients undergoing surgery. The study is an international, multicenter observational cohort where no treatment interventions are given. It includes children from neonates to adolescents who are mechanically ventilated during general anesthesia. Researchers will observe ventilator settings such as mode, tidal volume, pressure, oxygen levels, and ventilation parameters 15 minutes after incision, as well as monitor any complications during surgery. Participants will be followed up to five days after surgery to assess the occurrence of PPCs, length of hospital stay, and any admission to pediatric or neonatal intensive care units. The study will collect detailed data on ventilation practices and patient outcomes to identify factors linked to complications and to develop a risk score for PPCs. This information may help improve care and reduce lung complications after surgery in children.
CONDITIONS
Brief Title
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Research Team
J
Jorinde Polderman, MD, PhD
D
David van Meenen, MD, PhD
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