Actively Recruiting
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2025-04-09
10000
Participants Needed
4
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.
CONDITIONS
Official Title
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 16 years or younger
- Undergoing general anesthesia
- Airway managed with endotracheal tube or laryngeal mask airway (LMA)
- Connected to a mechanical ventilator
- Minimum procedure duration of 15 minutes
You will not qualify if you...
- Undergoing surgery with extracorporeal circulation
- Receiving high frequency jet ventilation or high frequency oscillatory ventilation
- Sedation without airway management using a tube or supraglottic airway device
- Undergoing rigid bronchoscopy with spontaneous ventilation maintained
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Perth Children's Hospital
Perth, Australia
Not Yet Recruiting
2
IRCCS Istituto Giannina Gaslini
Genoa, Italy
Not Yet Recruiting
3
Amsterdam University Medical Centers
Amsterdam, Please Select, Netherlands, 1105AZ
Actively Recruiting
4
Universitatsspital Bern
Bern, Switzerland
Not Yet Recruiting
Research Team
J
Jorinde Polderman, MD, PhD
CONTACT
D
David van Meenen, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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