Actively Recruiting

Age: 18Years +
All Genders
NCT05521529

Cushing's Syndrome Before and After Treatment (CORRECT)

Led by University of Aarhus · Updated on 2025-04-04

20

Participants Needed

1

Research Sites

506 weeks

Total Duration

On this page

Sponsors

U

University of Aarhus

Lead Sponsor

A

Aarhus University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms. The hypotheses are: * Cushing's syndrome negatively impacts health-related quality of life (HRQoL) and physical functioning * Cushing's syndrome is associated with altered circadian rhythms at the whole body level and in peripheral target tissues. * These complications partially reverse following disease control.

CONDITIONS

Official Title

Cushing's Syndrome Before and After Treatment (CORRECT)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • New diagnosis of endogenous Cushing's syndrome within 2 months, including ACTH-dependent or ACTH-independent forms
  • Age greater than 18 years
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Active cancer
  • Iatrogenic or malignant cause of Cushing's syndrome such as adrenocortical carcinoma
  • Chronic heart failure classified as New York Heart Association class IV
  • Chronic kidney disease stage 3 or higher (eGFR less than or equal to 30 ml/min)
  • Liver disease in the form of cirrhosis
  • Considered unable to complete the study safely by the investigator

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Endocrinology and Internal Medicine

Aarhus, State, Denmark, 8200

Actively Recruiting

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Research Team

S

Simon Bøggild Hansen, MD

CONTACT

J

Jens Otto Lunde Jørgensen, Professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Cushing's Syndrome Before and After Treatment (CORRECT) | DecenTrialz