Actively Recruiting
Cycling-Based Aerobic Exercise Intervention for Individuals With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Led by University of Alberta · Updated on 2026-03-12
30
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
Sponsors
U
University of Alberta
Lead Sponsor
C
Cross Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
CYCLE-CIPN is a proof-of-concept study designed to evaluate whether a prescribed aerobic exercise intervention has the potential to reduce the symptoms and functional impact of CIPN. The small number of participants in the proposed study will allow us to make decisions on the feasibility ("go/no-go") of a future larger-scale trial. The protocol will assess feasibility and acceptability through recruitment, completion, adherence, program satisfaction, and safety. The study will also evaluate CIPN symptoms using both patient-reported and objective outcome measures, as well as fitness and quality of life outcomes. We aim to recruit 30 participants. The Health Research Board of Alberta Cancer Committee has approved this study. Participants will participate in a stationary cycling-based aerobic exercise program biweekly for 12 weeks. Exercise sessions will be supervised and progressive, between 30 and 60 minutes each.
CONDITIONS
Official Title
Cycling-Based Aerobic Exercise Intervention for Individuals With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Cancer diagnosis stage I to III
- Mild (grade 1) chemotherapy-induced peripheral neuropathy (CIPN)
- Currently receiving or have completed chemotherapy treatment for cancer
- Able to speak, read, and understand English
You will not qualify if you...
- Medical conditions causing additional neuropathy symptoms (e.g., diabetes)
- Any uncontrolled medical conditions
- Scheduled for surgery or radiation therapy during the study period
- Currently participating in an aerobic exercise training program
- Currently involved in another exercise-based research study
- Unable to provide signed informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Actively Recruiting
Research Team
C
Christopher Sellar, PhD
CONTACT
T
Trei Lindstrom, BSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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