Study of a 12-Week Supervised Cycling Exercise Program to Reduce Symptoms in Adults With Chemotherapy-Induced Peripheral Neuropathy

What this Trial Is About

Researchers are investigating whether a stationary cycling-based aerobic exercise program can help reduce symptoms and improve function in individuals with chemotherapy-induced peripheral neuropathy CIPN. This proof-of-concept study aims to assess the feasibility and acceptability of this exercise intervention by recruiting 30 participants with cancer who are either undergoing or have completed chemotherapy. The study will explore both patient-reported and objective outcomes related to CIPN, fitness, and quality of life. Participants will take part in a 12-week supervised aerobic exercise program involving stationary cycling sessions twice a week. Each week includes two types of sessions continuous cycling and high-intensity interval training HIIT, tailored to each participants fitness level based on baseline heart rate testing. Certified exercise physiologists will supervise small groups of participants during sessions lasting between 30 and 60 minutes. During the study, researchers will monitor recruitment rates, participant adherence, program satisfaction, and safety, alongside measuring CIPN symptoms and fitness changes through questionnaires and clinical assessments. Participants will complete assessments before and after the intervention, with data analyzed to guide future larger trials. The total participation time spans 12 weeks of exercise sessions plus assessments, with safety and satisfaction carefully tracked throughout.

Cycling-Based Aerobic Exercise Intervention for Individuals With Chemotherapy-Induced Peripheral Neuropathy (CIPN)