Actively Recruiting

Early Phase 1
Age: 18Years +
FEMALE
NCT07278986

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Led by Abramson Cancer Center at Penn Medicine · Updated on 2025-12-12

10

Participants Needed

2

Research Sites

171 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The research study is being done to assess the safety and ability of an investigational drug called CYTALUX (pafolacianine) and a special camera system for the detection of cancer in patients undergoing surgical resection for endometrial cancer.

CONDITIONS

Official Title

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated informed consent form
  • Age 18 years or older
  • Primary diagnosis of endometrial cancer
  • Scheduled for surgery to treat endometrial cancer
  • Ability to understand study requirements and agree to follow study rules and assessments
  • Willingness to stop folate or folic acid supplements at least 48 hours before study drug infusion
Not Eligible

You will not qualify if you...

  • Pregnancy or positive pregnancy test
  • Any medical condition that could risk participant safety as judged by the investigator
  • History of severe allergic reactions to products containing indocyanine green
  • Allergy to any component of CYTALUX
  • Any psychological, family, social, or geographic issues that could interfere with study compliance or follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Abramson Cancer Center at Penn Medicine

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

2

University of Pennsylvania Gynecologic Oncology Department

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

B

Brianna Aguilar

CONTACT

J

Joseph Agyemang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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