Actively Recruiting

Age: 1Day - 36Months
All Genders
NCT06522880

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Led by University of Massachusetts, Worcester · Updated on 2024-07-26

100

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

Sponsors

U

University of Massachusetts, Worcester

Lead Sponsor

M

ModernaTX, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of STAGE I of the CMV TransmIT Study is to determine the prevalence of CMV shedding in children up to and including 36 months of age in large group childcare centers and in staff who regularly work at the center. Participants will complete a health survey and provide one saliva sample for CMV PCR testing. In addition, infrastructure for the study will be developed (e.g. community engagement to build the network of centers, data pipelines, digital platform, sampling workflows) and participant sample collection at home will be piloted. These activities will inform the design of STAGE II.

CONDITIONS

Official Title

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

Who Can Participate

Age: 1Day - 36Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children up to and including 36 months old at time of consent
  • Parent or guardian has given written consent for saliva PCR screening
  • Children living in the same household may each enroll
  • Staff who regularly work inside the childcare center (average at least 5 days per year), including employed, contracted, volunteer, full or part time
  • Staff member has given written consent for saliva PCR screening
Not Eligible

You will not qualify if you...

  • Children 37 months old or older
  • Children under custody of the State Department of Children and Families
  • Staff who do not regularly work inside the center (less than 5 days per year)
  • Staff whose work is associated with but not regularly inside the center, such as bus drivers or food delivery staff

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UMass Chan Medical School

Worcester, Massachusetts, United States, 01655

Actively Recruiting

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Research Team

L

Laura Gibson, MD

CONTACT

K

Karen Del'Olio, MPH

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study | DecenTrialz