Actively Recruiting
CytOSorb TreatMent Of Critically Ill PatientS Registry: International Registry on the Use of CytoSorb in the Critical Care Setting
Led by CytoSorbents, Inc · Updated on 2025-09-11
3000
Participants Needed
28
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational registry studies the use of the CytoSorb device, a sorbent hemoperfusion system, in real-world critical care settings for patients with serious conditions such as septic shock, acute respiratory distress syndrome, trauma, and other life-threatening illnesses. The goal is to create a comprehensive data repository and reporting system to monitor and improve patient care quality when using this device in intensive care units. Participants will be those who have planned or actual use of the CytoSorb 300 mL device. The study collects data on the device's use without assigning specific treatments, serving as a scientific resource to evaluate outcomes like ICU and hospital mortality. This registry includes patients receiving the device in various critical care scenarios, excluding certain uses like antithrombotic removal or intraoperative cardiac surgery applications. During the study, data about patient outcomes through ICU discharge or hospital discharge will be collected and analyzed, typically over an average of 7 to 14 days. This includes monitoring ICU mortality and in-hospital mortality. The registry aims to support ongoing assessment of the device's use by gathering real-world patient information over time to help improve care practices in critical care environments.
CONDITIONS
Brief Title
CytOSorb TreatMent Of Critically Ill PatientS Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Planned or actual use of the CytoSorb 300 mL device
- Informed consent provided for participation in the prospective registry
You will not qualify if you...
- Use of the CytoSorb 300 mL device only for antithrombotic removal
- Use of the CytoSorb 300 mL device only during cardiac surgery intraoperatively
- Occurrence of complications or medical reasons after consent that contraindicate or make CytoSorb use inappropriate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 7 to 14 days
Participants receive treatment with the CytoSorb sorbent hemoperfusion system as part of routine critical care.
Visits during ICU and hospital stay as per routine care
Duration - Up to hospital discharge
Participants are observed for outcomes including ICU and in-hospital mortality after treatment with CytoSorb.
Follow-up visits during hospital stay as needed
Trial Site Locations
Total: 28 locations
1
Klinikum Klagenfurt am Wörthersee
Klagenfurt, Austria, 9020
Actively Recruiting
2
Medizinische Universität Wien
Vienna, Austria, 1090
Actively Recruiting
3
Universitätsklinikum Aachen
Aachen, Germany, 52074
Actively Recruiting
4
Herz- und Diabeteszentrum Nordrhein-Westfalen
Bad Oeynhausen, Germany, 32545
Actively Recruiting
5
Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil Bochum
Bochum, Germany, 44789
Actively Recruiting
6
Katholisches Klinikum Bochum, St. Josef-Hospital
Bochum, Germany, 44791
Actively Recruiting
7
Universitätsklinikum Essen, Medizinische Intensivtherapie
Essen, Germany, 45147
Actively Recruiting
8
Universitätsklinikum Essen, Nephrologie
Essen, Germany, 45147
Actively Recruiting
9
Universitätsklinikum Essen, Thorax- und Kardiovaskuläre Chirurgie
Essen, Germany, 45147
Actively Recruiting
10
Universitätsmedizin Göttingen, Allgemein-, Viszeral- und Kinderchirurgie
Göttingen, Germany, 37075
Actively Recruiting
11
Universitätsmedizin Göttingen, Herzzentrum Göttingen
Göttingen, Germany, 37075
Actively Recruiting
12
Klinikum Herford
Herford, Germany, 32049
Actively Recruiting
13
Universitätsklinikum Jena
Jena, Germany, 07747
Actively Recruiting
14
Klinikum Kassel
Kassel, Germany, 34125
Withdrawn
15
Universitätsklinikum Marburg
Marburg, Germany, 35043
Actively Recruiting
16
Kliniken Maria Hilf
Mönchengladbach, Germany, 41063
Terminated
17
Deutsches Herzzentrum München
München, Germany, 80636
Actively Recruiting
18
LMU Klinikum München
München, Germany
Actively Recruiting
19
Klinikum Oldenburg
Oldenburg, Germany, 26133
Actively Recruiting
20
Helios Dr. Horst Schmidt Kliniken Wiesbaden
Wiesbaden, Germany, 65199
Actively Recruiting
21
Ospedale Pediatrico Bambino Gesù
Roma, Italy, 00165
Terminated
22
IRCCS Ospedale Casa Sollievo della Sofferenza
San Giovanni Rotondo, Italy, 71013
Actively Recruiting
23
SP ZOZ Szpital Uniwersytecki w Krakowie
Krakow, Poland, 30-688
Actively Recruiting
24
Uniwersyteckim Spitalem Klinicznym im. Jana Mikulicza - Radeckiego we Wrocławiu
Wroclaw, Poland, 50-556
Actively Recruiting
25
Unidade Local de Saúde de Coimbra E.P.E
Coimbra, Portugal, 3004-561
Actively Recruiting
26
ULS São José, Hospital Curry Cabral
Lisbon, Portugal
Actively Recruiting
27
Hospital Universitari Vall d'Hebron
Barcelona, Barcelona, Spain, 08035
Actively Recruiting
28
Hospital Juan Ramón Jimenez
Huelva, Spain
Actively Recruiting
Research Team
R
Robert Wilke
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0