Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT04364373

D2 vs D3 Lymph Node Dissection for Left Colon Cancer

Led by Russian Society of Colorectal Surgeons · Updated on 2024-04-09

1381

Participants Needed

1

Research Sites

717 weeks

Total Duration

On this page

Sponsors

R

Russian Society of Colorectal Surgeons

Lead Sponsor

I

I.M. Sechenov First Moscow State Medical University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The efficiency of the D3 lymph node dissection is still controversial for left colon cancer patients. This study will try find difference in 5-year overall survival between D2 and D3 lymph node dissection. Investigation of the functional and short-term outcomes will clarify safety of the D3 lymph node dissection.

CONDITIONS

Official Title

D2 vs D3 Lymph Node Dissection for Left Colon Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient agrees to participate in the trial
  • Diagnosed with colon adenocarcinoma
  • Tumor located between the splenic flexure and rectosigmoid junction
  • Tumor stage cT3-4a,b
  • Clinical lymph node stage cN0-2
  • No distant metastasis (cM0)
  • Able to tolerate chemotherapy
  • ASA physical status classification 1 to 3
Not Eligible

You will not qualify if you...

  • Tumor invasion into tail of pancreas, stomach, small bowel, ureter, or urinary bladder (stages Tis - T2, T4b)
  • Preoperative tumor complications such as perforation or complete bowel obstruction
  • Previous radiotherapy or chemotherapy
  • Presence of synchronous or metachronous tumors
  • Women who are pregnant or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinic of coloproctology and minimally invasive surgery

Moscow, Russia, 119435

Actively Recruiting

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Research Team

V

Vladimir Balaban, Ph.D

CONTACT

I

Inna Tulina, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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