Actively Recruiting
Single Center Observational Study Using Spinal Laser Interstitial Thermal Therapy for Spine Metastases and Tumors
Led by Dartmouth-Hitchcock Medical Center · Updated on 2026-02-06
25
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a new treatment called spinal laser interstitial therapy for people with metastatic spinal tumors. This study aims to compare how well this laser therapy controls tumor growth locally with the results from traditional open surgery. The goal is to see if this less invasive laser treatment offers similar tumor control while monitoring safety. Participants will receive surgery using the Visualase Thermal Therapy System, a laser device designed to treat spinal tumors. This method is studied as an alternative to open decompression surgery, followed by spine stereotactic radiosurgery. The study focuses on tumors located in the T2-T12 segments of the spine. During the study, researchers will assess tumor control rates at 12 months after treatment. Neurologic function will also be evaluated before surgery and at 3, 6, 9, and 12 months post-operation. Participants will be closely monitored to track outcomes and safety throughout the follow-up period, which extends up to one year after treatment.
CONDITIONS
Brief Title
D20054;LITT for Spine Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histology confirmed spinal tumor involving the T2-T12 spine segments
- Indication for spine stereotactic radiosurgery or palliative intervention
- Normal neurologic exam at the time of presentation (Frankel grade E)
- Age 18 years or older
You will not qualify if you...
- Contraindication to MRI
- Any neurologic deficit
- Tumor spanning more than 3 consecutive vertebral segments
- Contraindication to general anesthesia
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 week
Participants undergo spine laser interstitial thermal therapy (sLITT) surgery using the Visualase Thermal Therapy System device followed by immediate post-operative care.
1 surgical visit and several immediate post-operative visits
Duration - 12 months
Participants are followed to evaluate neurologic function and local tumor control after surgery.
Visits at 3, 6, 9, and 12 months post-operatively
Trial Site Locations
Total: 1 location
1
Dartmouth Health
Lebanon, New Hampshire, United States, 03766
Actively Recruiting
Research Team
L
Lauren Sinks, MPH
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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