Actively Recruiting
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
Led by Ohio State University Comprehensive Cancer Center · Updated on 2025-11-05
140
Participants Needed
2
Research Sites
234 weeks
Total Duration
On this page
Sponsors
O
Ohio State University Comprehensive Cancer Center
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited. The successful treatment will target neurophysiologic mechanisms for restoring function while addressing patient-reported symptoms and participation in treatment. Toward this end, the investigators propose to study a noninvasive, social sensorimotor intervention - Adapted Argentine Tango - which targets motor control restoration, symptom alleviation, and treatment participation in concert.
CONDITIONS
Official Title
DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Breast Cancer (BC) diagnosis of Stage I-IV including metastatic disease
- completed taxane-based chemotherapy for BC at least 3 months ago (no limit on how long ago)
- symptomatic for chemotherapy-induced neuropathy (self-report)
- postural control score that indicates potential fall-risk
- able to understand and comply with directions associated with testing and study treatments
You will not qualify if you...
- pre-existing vestibular dysfunction
- poorly controlled diabetes (hgA1C>=8)
- non-ambulatory (assistive and prosthetic devices allowed)
- hearing impairment resulting in less than 10% hearing bilaterally
- contraindication to participate in the experimental physical activity per the treating oncologist due to additional condition (e.g., herniated disc, unstable bone metastases)
- currently in activity-based therapy (e.g., physical therapy, occupational therapy). May enroll if still meet eligibility criteria once activity-based therapy is complete.
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Yale University
New Haven, Connecticut, United States, 06520
Actively Recruiting
2
The Ohio State University
Columbus, Ohio, United States, 43220
Actively Recruiting
Research Team
L
Lise Worthen-Chaudhari, PhD, MFA, CMES
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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