Actively Recruiting
Dabrafenib and/or Trametinib Rollover Study
Led by Novartis Pharmaceuticals · Updated on 2026-04-20
100
Participants Needed
28
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is to provide access for patients who are receiving treatment with dabrafenib and/or trametinib in a Novartis-sponsored Oncology Global Development, Global Medical Affairs or a former GSK-sponsored study who have fulfilled the requirements for the primary objective, and who are judged by the investigator as benefiting from continued treatment in the parent study as judged by the Investigator at the completion of the parent study.
CONDITIONS
Official Title
Dabrafenib and/or Trametinib Rollover Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is currently receiving treatment with dabrafenib/trametinib monotherapy or combination within a Novartis or former GSK sponsored study which has fulfilled the requirements for the primary objective.
- In the opinion of the Investigator would benefit from continued treatment.
You will not qualify if you...
- Patient has been previously permanently discontinued from study treatment in the parent protocol.
- Patient's indication is commercially available and reimbursed in the local country.
- Patient currently has unresolved toxicities for which dabrafenib and/or trametinib dosing has been interrupted in the parent study.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 28 locations
1
Honor Health Research Institute
Scottsdale, Arizona, United States, 85258
Active, Not Recruiting
2
Honor Health Research Institute
Scottsdale, Arizona, United States, 85258
Actively Recruiting
3
National Institute Of Health
Bethesda, Maryland, United States, 20892
Active, Not Recruiting
4
James Cancer Hospital and Solove Research Institute Ohio State
Columbus, Ohio, United States, 43210
Completed
5
Mary Crowley Cancer Research
Dallas, Texas, United States, 75251
Completed
6
Novartis Investigative Site
Caba, Buenos Aires, Argentina, C1121ABE
Completed
7
Novartis Investigative Site
Innsbruck, Tyrol, Austria, 6020
Active, Not Recruiting
8
Novartis Investigative Site
Beijing, China, 100036
Completed
9
Novartis Investigative Site
Copenhagen, Denmark, DK-2100
Active, Not Recruiting
10
Novartis Investigative Site
Lyon, France, 69373
Active, Not Recruiting
11
Novartis Investigative Site
Nantes, France, 44093
Active, Not Recruiting
12
Novartis Investigative Site
Paris, France, 75970
Completed
13
Novartis Investigative Site
Villejuif, France, 94800
Completed
14
Novartis Investigative Site
Mannheim, Baden-Wurttemberg, Germany, 68305
Completed
15
Novartis Investigative Site
Berlin, Germany, 13353
Completed
16
Novartis Investigative Site
Hamburg, Germany, 20246
Completed
17
Novartis Investigative Site
Heidelberg, Germany, 69120
Active, Not Recruiting
18
Novartis Investigative Site
Debrecen, Hajdu Bihar Megye, Hungary, 4032
Completed
19
Novartis Investigative Site
Budapest, Hungary, H 1122
Completed
20
Novartis Investigative Site
Kashiwa, Chiba, Japan, 277-8577
Completed
21
Novartis Investigative Site
Chuo Ku, Tokyo, Japan, 1040045
Completed
22
Novartis Investigative Site
Rotterdam, South Holland, Netherlands, 3015 GD
Completed
23
Novartis Investigative Site
Utrecht, Netherlands, 3584 CX
Active, Not Recruiting
24
Novartis Investigative Site
Barcelona, Spain, 08035
Actively Recruiting
25
Novartis Investigative Site
Madrid, Spain, 28040
Actively Recruiting
26
Novartis Investigative Site
Madrid, Spain, 28041
Completed
27
Novartis Investigative Site
Madrid, Spain, 28050
Actively Recruiting
28
Novartis Investigative Site
Songkhla, Hat Yai, Thailand, 90110
Active, Not Recruiting
Research Team
N
Novartis Pharmaceuticals
CONTACT
N
Novartis Pharmaceuticals
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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