Actively Recruiting
Daily Aspirin Treatment After Preeclampsia
Led by Anna Stanhewicz, PhD · Updated on 2025-12-15
40
Participants Needed
1
Research Sites
134 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent this disease progression. This study addresses this public health issue by examining whether starting low dose aspirin therapy after pregnancy is an effective treatment for lasting blood vessel damage in order to inform better clinical management of cardiovascular disease risk in women who have had preeclampsia.
CONDITIONS
Official Title
Daily Aspirin Treatment After Preeclampsia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Had preeclampsia in the past 5 years
- 18 years or older
You will not qualify if you...
- Current daily aspirin use
- Skin diseases
- Current tobacco or nicotine use, including vaping
- Diagnosed or suspected hepatic or metabolic disease including chronic kidney disease with eGFR less than 60 mL/min/1.73m2
- Use of statins or other cholesterol-lowering medications
- Current use of antihypertensive medication
- History of hypertension before pregnancy
- History of gestational diabetes
- Currently pregnant
- Body mass index less than 18.5 kg/m2
- Allergy to materials used during the study (e.g., latex)
- Known allergies to study drugs
- Bleeding disorders, peptic ulcer disease, gastritis, gastrointestinal bleeding, or gastroesophageal reflux disease
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Iowa
Iowa City, Iowa, United States, 52242
Actively Recruiting
Research Team
A
Anna Reid-Stanhewicz, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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