Evaluating DANCEREX Digital Dance Therapy for Adults with Multiple Sclerosis or Mild Cognitive Impairment

What this Trial Is About

Researchers are evaluating a new digital therapeutic solution called DANCEREX-DTx for people with chronic neurological disorders like Multiple Sclerosis and early signs of Mild Cognitive Impairment or risk of Alzheimers Disease. The study aims to test if this combined dance and music rehabilitation program with a motivational system improves treatment adherence, clinical and functional outcomes, quality of life, and usability compared to standard dance programs or educational sessions. Participants will be randomly assigned to one of three groups the experimental group using DANCEREX-DTx with 24 dance-based sessions supported by a motivational game system, an active comparator group receiving the same 24 dance sessions without the motivational system, or a placebo group watching educational videos. Each group will follow a 12-week program with two 45-minute sessions per week delivered via a tablet at home, progressing from seated to standing dance movements. During the study, researchers will monitor treatment adherence over the 12 weeks and assess various cognitive functions, balance, aerobic capacity, mood, health status, fatigue, depression, and anxiety at the start, after treatment, and up to six months later. Participants will complete tests like the Montreal Cognitive Assessment, Trail Making Test, and 6-Minute Walking Test. The study also tracks quality of life and motivation levels to evaluate the overall impact and acceptability of the digital rehabilitation approach.

The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders