Actively Recruiting
Eosinophils and Inflammation, an Expanded Study
Led by Children's Hospital Medical Center, Cincinnati · Updated on 2025-09-17
5000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the underlying mechanisms of eosinophil growth, survival, migration, and function. This study aims to better understand the pathophysiology, clinical symptoms, and range of severity in diseases caused by eosinophilic inflammation in humans. It is an observational study sponsored by the Children's Hospital Medical Center, Cincinnati. Participants will not receive any treatment as part of this study since it is observational. The study involves collecting data and samples to analyze eosinophilic disorders and related conditions such as eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, and food allergies. There are no specific intervention groups or treatments assigned. During the study, participants will provide informed consent, and if minors aged 11 or older, assent will also be obtained. The study includes individuals diagnosed with eosinophilic or food allergy conditions, their family members, or healthy controls. Researchers will collect and analyze clinical and biological data to better characterize these diseases. Participation involves observational assessments and sample collection with long-term follow-up possible, lasting until 2050.
CONDITIONS
Brief Title
Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent obtained from the patient or parent/guardian
- Assent obtained from minors 11 years of age and older
- Diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy, or being a family member or normal control
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Ongoing during study participation
Participants provide biological samples to help elucidate mechanisms of eosinophilic disorders.
Duration - Up to study completion in 2050
Participants are observed over time to monitor disease status and progression.
Trial Site Locations
Total: 1 location
1
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229-3039
Actively Recruiting
Research Team
B
Bliss Magella
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here