Study to Understand Eosinophilic Disorders and Inflammation Including Eosinophilic Gastrointestinal Disease and Food Allergy

What this Trial Is About

Researchers are investigating the underlying mechanisms of eosinophil growth, survival, migration, and function. This study aims to better understand the pathophysiology, clinical symptoms, and range of severity in diseases caused by eosinophilic inflammation in humans. It is an observational study sponsored by the Childrens Hospital Medical Center, Cincinnati. Participants will not receive any treatment as part of this study since it is observational. The study involves collecting data and samples to analyze eosinophilic disorders and related conditions such as eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, and food allergies. There are no specific intervention groups or treatments assigned. During the study, participants will provide informed consent, and if minors aged 11 or older, assent will also be obtained. The study includes individuals diagnosed with eosinophilic or food allergy conditions, their family members, or healthy controls. Researchers will collect and analyze clinical and biological data to better characterize these diseases. Participation involves observational assessments and sample collection with long-term follow-up possible, lasting until 2050.

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders