Actively Recruiting
Database Registry for Neural Network Biomarkers in Psychosis
Led by University of Texas Southwestern Medical Center · Updated on 2026-04-23
1000
Participants Needed
1
Research Sites
995 weeks
Total Duration
On this page
Sponsors
U
University of Texas Southwestern Medical Center
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Several observations have been made with magnetic resonance imaging (MRI) that characterize brain connections and brain function in individuals with schizophrenia and other mental disorders. For example, research investigating schizophrenia focuses on the dysfunction of connections within and between the medial temporal lobe and the prefrontal cortex as well as other pertinent brain regions. This database registry will allow for the collection of clinical interview data, behavioral data, blood, magnetic resonance imaging (MRI) data, and functional magnetic resonance imaging (fMRI) data on individuals with and without mental disorders to better understand how connections in the brain and various brain regions function differently while volunteers perform various cognitive tasks. This is an observational study that is being conducted to collect data and place it in a registry for current and future investigational questions related to imaging in mental disorders.
CONDITIONS
Official Title
Database Registry for Neural Network Biomarkers in Psychosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Volunteers with a DSM-IV-TR diagnosis of Schizophrenia or Schizoaffective disorder
- Competent to give informed consent
- All races and ethnicities eligible
- Eyesight corrected to 20-40 or better
- Able to read, speak, and understand English
- Healthy volunteers with no past or current severe mental illness
- Healthy volunteers with eyesight corrected to 20-40 or better
- Healthy volunteers able to read, speak, and understand English
You will not qualify if you...
- Diagnosis of an organic brain disease
- Diagnosis of alcohol or substance abuse in the last month or dependence in the last three months
- Serious, unstable medical illness
- History of serious head injury
- Pregnant women
- Healthy volunteers with history of psychiatric illness
- Healthy volunteers currently using psychoactive drugs other than nicotine and caffeine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75390
Actively Recruiting
Research Team
E
Elena Ivleva, M.D., Ph.D.
CONTACT
D
Debra Bushong, M.S., L.P.C.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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