Actively Recruiting

All Genders
NCT07293897

A Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)

Led by Takeda · Updated on 2026-02-20

50

Participants Needed

1

Research Sites

284 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a database study in Japan for maralixibat (TAK-625) used to treat participants with Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC). The main aim of the study is to evaluate the risk of liver disorder during the use of maralixibat in Japanese patients with ALGS or PFIC. This database study will conduct in use of medical database called Comprehensive and Informative Registry system for Childhood Liver Disease (CIRCLe).

CONDITIONS

Official Title

A Database Study of Maralixibat (TAK-625) in Participants With Alagille Syndrome (ALGS) and Progressive Familial Intrahepatic Cholestasis (PFIC)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Has a diagnosis of ALGS or PFIC within the enrollment period.
  • There is a prescription for Livmarli during the enrollment period (Index date: the date of the first prescription within the enrollment period).
Not Eligible

You will not qualify if you...

  • None

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Takeda selected site

Tokyo, Tokyo, Japan

Actively Recruiting

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Research Team

T

Takeda Contact

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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