Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
Healthy Volunteers
NCT03581604

De-labeling of Patients With False Diagnosis of Penicillin Allergy

Led by Oslo University Hospital · Updated on 2023-11-03

200

Participants Needed

1

Research Sites

485 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to estimate the prevalence of penicillin allergy, evaluate the diagnostic value of the allergologic work-up used in the study, and the health effects of penicillin allergy.

CONDITIONS

Official Title

De-labeling of Patients With False Diagnosis of Penicillin Allergy

Who Can Participate

Age: 18Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients referred to Pulmonary Medicine with suspected penicillin allergy
  • Healthy adult volunteers with no personal or family history of drug allergy, atopy, inflammatory, or autoimmune diseases
Not Eligible

You will not qualify if you...

  • History of systemic reactions such as DRESS or internal organ involvement
  • History of Type II-III hypersensitivity reactions
  • Severe Type IV hypersensitivity reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, vasculitis, or acute generalized exanthematous pustulosis
  • Chronic idiopathic urticaria on antihistamine maintenance or anti-IgE treatment
  • Use of medications affecting test outcomes
  • Active uncontrolled underlying diseases such as asthma
  • Cardiac disease with increased risk of serious anaphylaxis
  • Pregnancy or breastfeeding
  • Allergic reaction within the last 4-6 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Oslo University Hospital, Dpt of Pulmonary Diseases, Ullevål

Oslo, Postbox 4950 Nydalen, Norway, 0424

Actively Recruiting

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Research Team

E

Eva Stylianou, Phd

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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