Actively Recruiting

Phase Not Applicable
Age: 45Years - 64Years
All Genders
Healthy Volunteers
NCT05149742

Deafness and Cognition in Middle-aged Adults

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-09-15

180

Participants Needed

1

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing loss and patients with normal hearing in patients aged 45 to 64 years.

CONDITIONS

Official Title

Deafness and Cognition in Middle-aged Adults

Who Can Participate

Age: 45Years - 64Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 45 to 64 years with severe to profound bilateral post-lingual sensorineural hearing loss
  • Maximum speech intelligibility of 70% for disyllabic words in silence with hearing aids at 60 dB SPL, French-speaking
  • Healthy controls with normal hearing matched on age, sex, and education level
Not Eligible

You will not qualify if you...

  • Any disability preventing test performance
  • Past or current neurological or psychiatric disorders, including meningitis
  • Current use of psychotropic drugs
  • Vulnerable subjects

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre de Recherche en Audiologie (CReA) - Groupe Hospitalier Pitié-Salpêtrière

Paris, France, 75013

Actively Recruiting

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Research Team

I

Isabelle Dr MOSNIER, MD

CONTACT

N

Nassima SCHMOLL

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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Deafness and Cognition in Middle-aged Adults | DecenTrialz