Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07387107

Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults

Led by Heart and Brain Research Group, Germany · Updated on 2026-03-13

52

Participants Needed

1

Research Sites

18 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is a non-clinical substudy conducted within the DESTRESS research program (NCT05036538), which investigates the effects of relaxation interventions on physiological and psychological parameters. While the main DESTRESS trial focuses on cardiac surgical patients, this additional study arm examines the same interventions in a non-clinical adult population under controlled conditions, independent of disease-, surgery-, or medication-related influences. Participants are randomly assigned to one of several experimental conditions and take part in a single approximately 30-minute session. Depending on group allocation, the session may include exposure to natural soundscapes, natural soundscapes combined with binaural beats, virtual reality-based natural environments, virtual reality combined with binaural beats, or a control condition without a relaxation intervention. The primary aim of the DESTUD-Study is to assess the feasibility and potential stress-reducing effects of these non-pharmacological relaxation approaches in a non-clinical setting and to support the interpretation of findings from the clinical DESTRESS trial. Physiological responses, including heart rate variability and electrodermal activity, as well as self-reported stress measures, are collected before, during and after the conditions.

CONDITIONS

Official Title

Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Ability to understand study procedures and provide written informed consent
  • Sufficient proficiency in the German language to complete questionnaires and follow study instructions
  • Willingness to participate in a single approximately 60-minute study session
Not Eligible

You will not qualify if you...

  • Current or history of neurological or psychiatric disorders that may interfere with data collection (e.g., dementia, major depressive disorder, stroke, epilepsy)
  • Severe visual or hearing impairments that would limit the use of virtual reality equipment or headphones
  • History of adverse reactions to virtual reality

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kerckhoff-Clinic

Bad Nauheim, Germany, 61231

Actively Recruiting

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Research Team

M

Marius Butz, PhD, M.Sc.

CONTACT

R

Rolf Meyer, M.Sc.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

PREVENTION

Number of Arms

5

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