Actively Recruiting
Deep Brain Stimulation (DBS) for Obsessive Compulsive Disorder (OCD): Improving Targeting Precision
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2024-07-10
10
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
When comparing targeting precision between DBS in parkinsonian patients and OCD patients, an unexpected deviation from the planned targets was discovered in OCD patients (Nuttin et al., 2013). The objective of this trial is to investigate whether the use of a micro-electrode assisted technique improves targeting precision in DBS at the BNST.
CONDITIONS
Official Title
Deep Brain Stimulation (DBS) for Obsessive Compulsive Disorder (OCD): Improving Targeting Precision
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of OCD following DSM-IV criteria (300.3)
- Documented failure of pharmacotherapy trials following OCD treatment guidelines
- Documented failure of cognitive and behavioral therapy
- Duration of illness of at least 5 years
- Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score of at least 30 out of 40
- Age between 20 and 65 years
You will not qualify if you...
- Severe personality disorder in cluster A or B with high risk for acting-out behavior
- Organic brain pathology or significant abnormalities on MRI
- Present or past history of psychotic symptoms
- Current substance abuse or unstable remission within the last 12 months
- Any disorder affecting cognitive function other than motor tics or Gilles de la Tourette's Syndrome
- Mental retardation preventing adequate questionnaire reporting and instrument handling
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
B
Bart Nuttin, MD, PHD
CONTACT
S
Simon Raymaekers, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here