Actively Recruiting

Age: 18Years - 100Years
All Genders
Healthy Volunteers
NCT06839443

Deep Learning in the Detection and Prediction of Hydroxychloroquine Maculopathy

Led by Centro Hospitalar de Lisboa Central · Updated on 2025-02-21

100

Participants Needed

1

Research Sites

46 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hydroxychloroquine retinal toxicity affects a significant number of patients using this medication. Detection of toxicity is difficult in the early stages of the disease and depends on the subjectivity of the clinician who reads the tests (optical coherence tomography, autofluorescence and visual fields). Automating the reading of these diagnostic exams could lead to earlier detection of this pathology and reduce the burden associated with interpreting these exams in the ophthalmology service. The images that are usually taken in the screening and monitoring of hydroxychloroquine toxicity by will be collected - photography of the ocular fundus and optical coherence tomography with autofluorescence.

CONDITIONS

Official Title

Deep Learning in the Detection and Prediction of Hydroxychloroquine Maculopathy

Who Can Participate

Age: 18Years - 100Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with > 10 years of HCQ intake
Not Eligible

You will not qualify if you...

  • Patients with ocular diseases that might mimic HCQ maculopathy or interfere with HCQ maculopathy screening

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Local de Saúde São José

Portugal, Portugal, 1150-199

Actively Recruiting

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Research Team

R

Rita Anjos, MD

CONTACT

A

Ana Luisa Basílio, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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