Actively Recruiting
Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy
Led by Anqing Municipal Hospital · Updated on 2024-06-24
72
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
BACKGROUND: Some studies have revealed that deep neuromuscular block (NMB) improve surgical conditions and alleviated postoperative pain compared with moderate NMB. The present study investigated deep NMB could improve the quality of recovery after laparoscopic hysterectomy METHODS: seventy-two women with elective laparoscopic hysterectomy were randomly divided into 2 groups: Patients in group A received low-pressure pneumoperitoneum (LPP), which was set at 8-10 mmHg with deep NMB. Patients in group B received standard-pressure pneumoperitoneum (SPP), which was set at 12-14 mmHg with moderate NMB. Primary outcome was the quality of recovery (QoR-15) at 1 day after sugery. The secondary outcomes included postoperative pain, surgical condition, incidence of shoulder pain, the incidence of rescue analgesic drug use, cumulative dose of analgesics, time of first flatus, post-operative nausea and vomiting, time of tracheal tube removal.
CONDITIONS
Official Title
Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18 to 65 years
- American Society of Anesthesiologists (ASA) physical status I to II
- Scheduled for elective laparoscopic hysterectomy
You will not qualify if you...
- Unable to give informed consent
- Body mass index (BMI) greater than 35
- Kidney or liver insufficiency
- History of preoperative psychiatric disorders
- Previous surgery at the procedure site
- Neuromuscular disease
- Pregnancy
- Contraindications to study medications
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Anqing Munucipal Hospital Anesthesiology
Anqing, Anhui, China, 246000
Actively Recruiting
Research Team
X
Xu si qi, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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