Actively Recruiting
Deep Rectus Sheath Block for Postoperative Pain Relief in Patients Undergoing Laparoscopic Cholecystectomy
Led by Istinye University · Updated on 2025-09-22
60
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the pain relief effects of a new technique called the deep rectus sheath block for patients undergoing laparoscopic cholecystectomy, a minimally invasive gallbladder removal surgery. This study focuses on comparing this novel block with standard postoperative pain management methods to see if it can better reduce pain and the need for additional medication. The trial evaluates how the block may improve patient comfort after surgery and reduce side effects such as nausea and vomiting. Participants are randomly assigned to one of two groups. The control group receives patient-controlled analgesia with morphine for pain management after surgery. The other group receives the deep rectus sheath block at the end of the surgery along with the same morphine patient-controlled analgesia. Researchers will track the amount of morphine used in the first 24 hours after surgery and compare pain scores between the groups. During the study, patients will be monitored for morphine consumption, numerical pain scores, use of additional rescue pain medication, and the occurrence of nausea or vomiting within the first 24 hours after surgery. The study uses a double-blind design to ensure unbiased results. The total participation involves surgery and postoperative monitoring, with the primary focus on pain control and side effects within one day after the procedure.
CONDITIONS
Brief Title
Deep Rectus Sheath Block for Laparoscopic Cholecystectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Patients with American Society of Anesthesiology (ASA) physical status I-II
- Patients scheduled for a laparoscopic cholecystectomy
You will not qualify if you...
- Allergy to local anesthetics
- Coagulopathy
- Skin infection at the deep rectus sheath block area
- Advanced hepatic or renal failure
- Chronic pain syndromes
- Alcohol or drug abuse
- Severe pulmonary and/or cardiovascular disease
- Psychiatric disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery and immediate recovery
Participants undergo laparoscopic cholecystectomy surgery. Those in the Deep Rectus Sheath Block Group receive a deep rectus sheath block at the end of surgery, along with patient controlled analgesia with morphine. Participants in the Control Group receive patient controlled analgesia with morphine alone for postoperative pain relief.
1 surgery visit and immediate post-operative care
Duration - 24 hours after surgery
Participants are monitored for postoperative pain relief, morphine consumption, need for rescue analgesics, and incidence of nausea and vomiting during the first 24 hours after surgery.
1 follow-up visit within 24 hours post-surgery
Trial Site Locations
Total: 1 location
1
Istinye University Hospital
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
T
Taylan Sahin, M.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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