Actively Recruiting
Deep TMS of Neural Circuits Associated With Stimulant Use Disorder
Led by Stanford University · Updated on 2025-09-12
30
Participants Needed
1
Research Sites
93 weeks
Total Duration
On this page
Sponsors
S
Stanford University
Lead Sponsor
V
VA Palo Alto Health Care System
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to evaluate the efficacy of deep transcranial magnetic stimulation (dTMS) as a treatment for Veterans with a methamphetamine use disorder (MUD).
CONDITIONS
Official Title
Deep TMS of Neural Circuits Associated With Stimulant Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must be within the age range of 25-75.
- Must meet DSM-5 criteria for moderate to severe methamphetamine use disorder (4 or more diagnostic symptoms).
- Must be able to obtain a Motor Threshold during screening.
- Must have a stable condition and environment to attend scheduled clinic visits.
- Must be able to read, verbalize, understand, and voluntarily sign the informed consent form in English.
- If on medication for other symptoms, must have a stable regimen and agree to remain on it during treatment.
- Must be fluent in English.
You will not qualify if you...
- Contraindications to TMS or MRI such as having a cardiac pacemaker, cochlear implant, deep brain stimulation device, ferromagnetic metal near head or body, claustrophobia, pregnancy or breastfeeding.
- Medical, neurological, or psychiatric conditions that interfere with participation.
- Unable to safely stop medications increasing seizure risk at least two weeks before treatment.
- Current substance abuse as shown by positive toxicology screen.
- Presence of mass lesion, cerebral infarct, active CNS disease, or seizure disorder.
- Recent suicide attempt within 30 days or current suicidal plan or intent without a safety plan.
- Severe vision, hearing, or hand movement impairments interfering with study.
- History of more than mild traumatic brain injury (more than 10 minutes loss of consciousness).
- Use of benzodiazepines, neuroleptic medications, or any drugs that alter seizure threshold.
- Acute or unstable chronic illness.
- Current or lifetime bipolar disorder or psychosis.
- Participation in another intervention-based clinical trial.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
VA Palo Alto Health Care System
Palo Alto, California, United States, 94304
Actively Recruiting
Research Team
S
Samantha Ward, BS
CONTACT
E
Eileen G Fischer, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here