Study to Identify Predictors of Diabetes After Kidney Transplant Using Continuous Glucose Monitoring

What this Trial Is About

Researchers are conducting a prospective, multicenter observational study to develop a tool that predicts the risk of post-transplant diabetes mellitus PTDM three months after kidney transplantation. The study aims to identify individual predictor variables on the day of transplantation and explore optimal combinations in predictive models. It also compares the new model with existing PTDM prediction models and investigates glucose level changes in the first two weeks post-transplant. Participants will undergo continuous glucose monitoring for the first 14 days after transplantation to track glucose levels. The study will analyze how these glucose patterns relate to baseline patient characteristics and immunosuppressant drug use. Researchers will evaluate whether adding glucose data from the early post-transplant period improves prediction accuracy and will identify predictors for early hyperglycemia. During the study, participants will be monitored for the development of PTDM at 10 to 13 weeks post-transplant. Data collection includes baseline information on transplantation day and glucose monitoring results. The study includes adult kidney transplant recipients receiving immunosuppressive therapy with tacrolimus and corticosteroids. The overall follow-up and participation duration align with the primary outcome assessment at about three months post-transplant.

Define Predictors for Posttransplant Diabetes Mellitus Study