Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07555574

Defining Retinal Structures Using Hyperspectral Retinal Imaging

Led by Center for Eye Research Australia · Updated on 2026-04-29

1000

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study evaluates hyperspectral retinal imaging as a novel, non-invasive imaging technique to characterise retinal and optic nerve structures in healthy individuals and patients with eye disease. Hyperspectral imaging captures retinal data across multiple wavelengths to generate detailed spectral information that may reveal features not visible with conventional retinal photography. Approximately 1000 participants will undergo multi-modal ophthalmic imaging in Melbourne, Australia, including hyperspectral imaging, OCT, fundus photography, and related tests. The study aims to compare hyperspectral imaging with standard imaging methods and assess its ability to identify retinal biomarkers associated with diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration.

CONDITIONS

Official Title

Defining Retinal Structures Using Hyperspectral Retinal Imaging

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years and older
  • Able to provide informed consent
  • Willing and able to attend a study visit at the Centre for Eye Research Australia
  • Participants with diagnosed retinal or optic nerve disease (e.g., diabetic retinopathy, glaucoma, age-related macular degeneration)
  • Age- and sex-matched healthy control participants without known retinal or optic nerve disease
Not Eligible

You will not qualify if you...

  • Inability to provide informed consent
  • Ocular conditions preventing adequate retinal imaging (e.g., dense cataract, severe corneal opacity, vitreous haemorrhage)
  • Known contraindication to pharmacological pupil dilation
  • History of narrow anterior chamber angle or risk of angle closure glaucoma where dilation is considered unsafe
  • Any condition that, in the investigator's opinion, would compromise participant safety or image quality

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Centre for Eye Research Australia

Melbourne, Victoria, Australia, 3002

Actively Recruiting

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Research Team

D

Darvy Dang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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