Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05646576

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Led by Massachusetts General Hospital · Updated on 2026-04-21

90

Participants Needed

1

Research Sites

221 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

C

Conquer Cancer Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to determine whether a palliative care intervention (PEACE) can improve the quality of life and experiences of participants with Lymphoma, Leukemia, or Multiple Myeloma receiving adoptive cellular therapy (ACT). After completion of an open pilot, participants will be randomly assigned into one of two study intervention groups. The names of the study intervention groups involved in this study are: * Palliative care (PEACE) plus usual oncology care * Usual care (standard oncology care) Participation in this research study is expected to last for up to 2 years. It is expected that about 90 people will take part in this research study.

CONDITIONS

Official Title

Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Ability to complete surveys in English or with assistance of an interpreter
  • Diagnosis of a hematologic malignancy
  • Receiving autologous adoptive cellular therapy (ACT) at MGH with an FDA approved cellular therapy product
Not Eligible

You will not qualify if you...

  • Impaired cognition or uncontrolled mental illness that prevents study participation based on oncology clinician assessment
  • Currently receiving palliative care

AI-Screening

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

P

Patrick C Johnson

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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