Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT07122713

Definitive Radiation Therapy for Inoperable Breast Cancer

Led by Alexander Stessin · Updated on 2025-12-17

30

Participants Needed

1

Research Sites

420 weeks

Total Duration

On this page

Sponsors

A

Alexander Stessin

Lead Sponsor

N

Northwell Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.

CONDITIONS

Official Title

Definitive Radiation Therapy for Inoperable Breast Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Biopsy proven invasive carcinoma of the breast, including lobular, ductal, or no special type
  • Tumor stages T1 to T4, lymph node stages N0 to N2, and M0 to M1 invasive breast carcinoma by clinical or radiological criteria
  • Cancer is considered unresectable, or patient is not a surgical candidate, or patient declines surgery after surgical evaluation
  • Life expectancy greater than 6 months
  • Negative pregnancy test at treatment start for any female of reproductive age
Not Eligible

You will not qualify if you...

  • Receiving concurrent systemic therapy except endocrine therapy, HER2-targeted therapy, or immunotherapy which are allowed
  • Previous radiation therapy to the same breast or regional lymph nodes
  • Unable to undergo study treatment planning or treatment due to body habitus

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stony Brook University Cancer Center

Stony Brook, New York, United States, 11794

Actively Recruiting

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Research Team

C

Caterina Stony Brook Cancer Center Clinical Trials

CONTACT

C

Caterina Vacchi-Suzzi, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Definitive Radiation Therapy for Inoperable Breast Cancer | DecenTrialz