Actively Recruiting

Age: 18Years +
All Genders
NCT06481449

Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer (ChC&UES): A Multi-center Real World Study

Led by Hebei Medical University Fourth Hospital · Updated on 2024-07-01

2600

Participants Needed

1

Research Sites

1300 weeks

Total Duration

On this page

Sponsors

H

Hebei Medical University Fourth Hospital

Lead Sponsor

T

Tianjin Medical University Cancer Institute and Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cervical and upper thoracic esophageal cancer (ESCA) presents treatment challenges due to limited clinical evidence. This multi-center study (ChC\&UES) explores radical radio(chemo)therapy efficacy and safety

CONDITIONS

Official Title

Definitive Radiotherapy for Cervical and Upper Thoracic Esophageal Cancer (ChC&UES): A Multi-center Real World Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 and older
  • Confirmed esophageal cancer by histopathology or cytology
  • Primary tumor located in cervical or upper thoracic esophagus
  • No distant metastasis
  • Unable or unwilling to have surgical treatment
  • Receiving radical radiotherapy as first-line treatment with or without chemotherapy, immunotherapy, or targeted therapy
  • Undergoing conventional radiotherapy (1.8-2.0Gy per session, once daily)
  • Receiving 3DCRT or IMRT radiotherapy
  • Complete radiotherapy dose information and follow-up records available
Not Eligible

You will not qualify if you...

  • Radiation dose below 50Gy
  • History of other malignancies except cured cancer in situ or malignancies cured for more than 5 years
  • Laryngeal invasion
  • Diagnosis of double primary esophageal cancer
  • Chest radiation therapy within the past 5 years
  • Recurrent or metastatic esophageal cancer
  • Use of 2D radiotherapy, large fractionation, or hyper-fractionation radiotherapy
  • Incomplete radiotherapy dose or follow-up data

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Because this study is a response to real-world patient treatment and outcomes

Shijiazhuang, Hebei, China, 050000

Actively Recruiting

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Research Team

W

Wenbin Shen

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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