Actively Recruiting
Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe
Led by Santiago Ortega Gutierrez · Updated on 2026-03-13
2039
Participants Needed
6
Research Sites
117 weeks
Total Duration
On this page
Sponsors
S
Santiago Ortega Gutierrez
Lead Sponsor
P
Patient-Centered Outcomes Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to compare two strategies for treating adults with suspected large vessel occlusion stroke within 7 hours of symptom onset. Researchers will evaluate whether direct transfer to the neurointerventional angiography suite improves recovery and reduces disability compared to the conventional approach of first being evaluated in the emergency department. The study will also assess safety and other health outcomes to guide care for stroke patients.
CONDITIONS
Official Title
Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients With Large Vessel OCclusion in the Angiography SuiTe
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Signs or symptoms suggestive of acute large vessel occlusion stroke
- Baseline NIH Stroke Scale score of 10 or higher
- Arrival at a thrombectomy-capable stroke center within 7 hours from last known well
- For interfacility transfers, more than 90 minutes must have passed from first imaging to arrival at thrombectomy center
- For conventional triage arm: presence of qualifying LVO by CTA or MRA imaging or large core infarcts regardless of embolectomy decisions
- For direct transfer to angiography suite arm: enrollment regardless of LVO presence or embolectomy decisions
You will not qualify if you...
- Arrival at thrombectomy-capable center more than 7 hours from last known stroke
- For interfacility transfer patients, arrival within 90 minutes of imaging at outside hospital
- Presence of intracranial hemorrhage that makes thrombectomy unsafe in conventional strategy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
University of Iowa
Iowa City, Iowa, United States, 52242
Not Yet Recruiting
2
Henry Ford Health System
Detroit, Michigan, United States, 48202
Actively Recruiting
3
University of Michigan Health-West
Wyoming, Michigan, United States, 49519
Actively Recruiting
4
HMH Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
Actively Recruiting
5
The Research Foundation for SUNY on behalf of University at Buffalo
New York, New York, United States, 14203
Actively Recruiting
6
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Santiago Ortega, MD
CONTACT
C
Carlos A Contreras Mesa, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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