Actively Recruiting
Delineation of Target Volume of Stereotactic Radiotherapy for Spinal Tumors
Led by Peking University Third Hospital · Updated on 2024-09-19
500
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing two methods for defining the treatment area in stereotactic radiotherapy for patients with metastatic spinal tumors. This study aims to evaluate which target delineation method is better in terms of controlling the disease and reducing side effects. Approximately 500 patients with spinal tumors will participate in this bidirectional cohort study. Participants are divided into two groups based on how the treatment area is defined. Group 1 receives radiotherapy targeting only the local tumor, while Group 2's treatment area includes the local tumor plus the adjacent vertebral area. The study monitors these approaches to assess differences in treatment outcomes. During the study, patients will be followed up to assess disease control over two years and pain relief after three months. Side effects will also be tracked for two years. Participants will undergo imaging reviews and follow-up visits after radiotherapy to evaluate treatment effects and safety.
CONDITIONS
Brief Title
Delineation of Target Volume of Stereotactic Radiotherapy for Spinal Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with spinal metastases or primary tumors receiving stereotactic radiotherapy
- Patients with sufficient pre-treatment imaging data
- Patients who can cooperate with imaging review and follow-up after radiotherapy
You will not qualify if you...
- Patients with an expected survival of less than 3 months
- Patients with second-course radiotherapy
- Patients with physical conditions that cannot tolerate stereotactic radiotherapy
- Patients with extensive spinal metastasis and no local therapeutic value
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single treatment period as per clinical protocol
Participants receive stereotactic radiotherapy targeting either the local tumor only or the local tumor plus adjacent vertebral area depending on their group assignment.
1 treatment visit (in-person)
Duration - Up to 2 years
Participants are monitored for disease control, pain relief, and side effects after radiotherapy.
Follow-up visits over 2 years for assessment
Trial Site Locations
Total: 1 location
1
Department of Radiation Oncology Cancer Center, Peking University Third Hospital 49# North Garden Rd.,Haidian Dist.
Beijing, Beijing Municipality, China, 100191
Actively Recruiting
Research Team
H
Hongqing Zhuang, Doctor
Y
Yuxia Wang
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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