Actively Recruiting

Age: 65Years +
All Genders
NCT06326424

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Led by Ohio State University · Updated on 2025-04-03

60

Participants Needed

1

Research Sites

98 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Delirium is especially dangerous for persons living with Alzheimer Disease and Related Dementias (AD/ADRD). Persons living with ADRD have an almost 50% chance of developing delirium in the hospital. Clinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out delirium in acutely ill older patients. The investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delirium than current verbal screening tools.

CONDITIONS

Official Title

Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 65 years or older with a known diagnosis of dementia or a strong suspicion or confirmation of dementia during this visit
  • Emergency Department visit or hospitalization expected to last more than 4 hours from enrollment
Not Eligible

You will not qualify if you...

  • Currently intubated or on mechanical ventilation
  • Undergoing a procedure requiring sedation
  • Unable to consent due to cognitive impairment without a legally authorized representative or caregiver present

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States, 43210

Actively Recruiting

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Research Team

L

Lauren Southerland, MD MPH

CONTACT

M

Michael Hill, RN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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