Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT05373017

Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors

Led by University of Wisconsin, Madison · Updated on 2026-04-14

528

Participants Needed

6

Research Sites

228 weeks

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

I

Indiana University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will evaluate the usefulness of the Urgent and Emergency Surgery (UES) Delirium Recovery Model. It is hypothesized that the cognitive, physical and psychological recovery of older UES delirium survivors will be improved through the use of the DANE Recovery Model. Participants can expect to be on the study for 18 months.

CONDITIONS

Official Title

Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 65 years and older
  • Admitted to one of the participating hospitals
  • Underwent emergency or unplanned abdominal, orthopedic, skin, or vascular surgery
  • English-speaking
  • Able to provide consent or have a legally authorized representative to provide consent
  • Access to a telephone or an internet-connected computer or smart device
  • Discharged to home or sub-acute rehabilitation
  • Experienced at least one episode of delirium or subsyndromal delirium before discharge as identified by the Confusion Assessment Method-ICU (CAM-ICU)
Not Eligible

You will not qualify if you...

  • Self-reported diagnosis of cancer with short life expectancy
  • History of dementing illnesses or neurodegenerative diseases such as Alzheimer's disease, Parkinson disease, or vascular dementia
  • Current use of anti-dementia medication or dementia ruled out by Functional Activities Questionnaire (FAQ) score
  • History of significant traumatic brain injury
  • Acute or subacute neurologic deficits expected to prevent independent living after discharge
  • Spinal cord injury with persistent neurologic deficit at enrollment
  • Incarcerated or homeless at enrollment
  • Acquired neurologic injury (stroke, traumatic brain injury, cerebral edema/swelling, anoxic brain injury, or other severe neurologic deficits) as admitting diagnosis or new event during hospitalization
  • History of bipolar disorder or schizophrenia confirmed by medical records

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

SwedishAmerican Hospital

Rockford, Illinois, United States, 61104

Not Yet Recruiting

2

Indiana University

Indianapolis, Indiana, United States, 47405

Actively Recruiting

3

University of Wisconsin

Madison, Wisconsin, United States, 53705

Actively Recruiting

4

Meriter Hospital

Madison, Wisconsin, United States, 53715

Actively Recruiting

5

East Madison Hospital

Madison, Wisconsin, United States, 53718

Actively Recruiting

6

Medical College of Wisconsin

Milwaukee, Wisconsin, United States, 53226

Not Yet Recruiting

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Research Team

S

Sarah Robbins

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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