Actively Recruiting
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
Led by Alnylam Pharmaceuticals · Updated on 2026-04-24
2000
Participants Needed
4
Research Sites
249 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with vutrisiran in routine clinical care * Describe treatment patterns of adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess health-related quality of life (HRQOL) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care * Assess healthcare resource use (HCRU) in adult patients with ATTR-CM treated with vutrisiran in routine clinical care Compare the long-term effectiveness of vutrisiran versus other approved ATTR-CM treatments in routine clinical care
CONDITIONS
Official Title
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Has a diagnosis of ATTR-CM
- Is initiating treatment with vutrisiran or another approved ATTR-CM therapy
You will not qualify if you...
- Is enrolled in an interventional clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Clinical Trial Site
Naples, Florida, United States, 34102
Actively Recruiting
2
Clinical Trial Site
Boston, Massachusetts, United States, 02215
Actively Recruiting
3
Clinical Trial Site
New Brunswick, New Jersey, United States, 08901
Actively Recruiting
4
Clinical Trial Site
Memphis, Tennessee, United States, 38120
Actively Recruiting
Research Team
C
Clinical Trial Information Line
CONTACT
C
Clinical Trial Information Line
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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